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  <xsd:element name="StockholdersEquityNoteLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="fenc_StockholdersEquityNoteLineItems" substitutionGroup="xbrli:item" />
  <xsd:element name="PercentageOfCommonSharesOutstanding" type="dtr-types:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" id="fenc_PercentageOfCommonSharesOutstanding" substitutionGroup="xbrli:item" />
  <xsd:element name="FairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="fenc_FairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTable" substitutionGroup="xbrldt:hypercubeItem" />
  <xsd:element name="FairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="fenc_FairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisLineItems" substitutionGroup="xbrli:item" />
  <xsd:element name="RobertAndradeMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="fenc_RobertAndradeMember" substitutionGroup="xbrli:item" />
  <xsd:element id="fenc_ExpiryDateAxis" name="ExpiryDateAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_ExpiryDateDomain" name="ExpiryDateDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_EquityFinancingAxis" name="EquityFinancingAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_EquityFinancingDomain" name="EquityFinancingDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_ProcessaPharmaceuticalsIncMember" name="ProcessaPharmaceuticalsIncMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_LicenseAgreementMember" name="LicenseAgreementMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_CollaborativeArrangementSharesToBeIssued" name="CollaborativeArrangementSharesToBeIssued" nillable="true" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="fenc_MilestoneEventAxis" name="MilestoneEventAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_ShareRestrictionExpirationTrancheAxis" name="ShareRestrictionExpirationTrancheAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_ShareRestrictionExpirationTrancheDomain" name="ShareRestrictionExpirationTrancheDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_MilestoneEventDomain" name="MilestoneEventDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_EquityIncentivePlanMember" name="EquityIncentivePlanMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element name="DiscountsForPromptPayment" id="fenc_DiscountsForPromptPayment" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfPromptPaymentDiscountsExpectedToPayOut" id="fenc_PercentageOfPromptPaymentDiscountsExpectedToPayOut" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="GrossProductRevenue" id="fenc_GrossProductRevenue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ChargebacksDiscountsForPromptPayAndOtherAllowancesMember" id="fenc_ChargebacksDiscountsForPromptPayAndOtherAllowancesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="RebatesCustomerFeesCreditsAndCoPayAssistanceMember" id="fenc_RebatesCustomerFeesCreditsAndCoPayAssistanceMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DiscountsAndAllowancesProvisionForCurrentPeriodSales" id="fenc_DiscountsAndAllowancesProvisionForCurrentPeriodSales" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DiscountsAndAllowancesPaymentsAndCustomerCreditsIssued" id="fenc_DiscountsAndAllowancesPaymentsAndCustomerCreditsIssued" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ManufacturingCostsCapitalizedToInventory" id="fenc_ManufacturingCostsCapitalizedToInventory" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ManufacturingCostsCapitalizedToInventoryWorkInProcess" id="fenc_ManufacturingCostsCapitalizedToInventoryWorkInProcess" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ManufacturingCostsCapitalizedToInventoryFinishedGoods" id="fenc_ManufacturingCostsCapitalizedToInventoryFinishedGoods" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LeaseContingenciesMember" id="fenc_LeaseContingenciesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ExecutiveSeveranceMember" id="fenc_ExecutiveSeveranceMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfSeverancePayments" id="fenc_NumberOfSeverancePayments" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="TriangleParkNorthCarolinaMember" id="fenc_TriangleParkNorthCarolinaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="HobokenNewJerseyMember" id="fenc_HobokenNewJerseyMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OfficeServiceAgreementMember" id="fenc_OfficeServiceAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OperatingLeaseDaysNoticeRequiredToTerminateAgreement" id="fenc_OperatingLeaseDaysNoticeRequiredToTerminateAgreement" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="OperatingLeasePenaltiesAndContingentPaymentsPayable" id="fenc_OperatingLeasePenaltiesAndContingentPaymentsPayable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProvisionForDiscountsAndAllowances" id="fenc_ProvisionForDiscountsAndAllowances" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ManufacturingCostsCapitalizedToInventoryRawMaterials" id="fenc_ManufacturingCostsCapitalizedToInventoryRawMaterials" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ProductSalesDiscountsAndAllowancesPolicyTextBlock" id="fenc_ProductSalesDiscountsAndAllowancesPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="RefundsDiscountsAndAllowances" id="fenc_RefundsDiscountsAndAllowances" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LicenseAgreementFundingReceived" id="fenc_LicenseAgreementFundingReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LicenseAgreementFundingPotentialMilestonePayments" id="fenc_LicenseAgreementFundingPotentialMilestonePayments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ExclusiveLicensingAgreementMember" id="fenc_ExclusiveLicensingAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NorgineLtdMember" id="fenc_NorgineLtdMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LicenseAgreementPolicyPolicyTextBlock" id="fenc_LicenseAgreementPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="IncrementalCostsCapitalizedToOtherNonCurrentAssets" id="fenc_IncrementalCostsCapitalizedToOtherNonCurrentAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="IncrementalCostsPaid" id="fenc_IncrementalCostsPaid" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CostOfProductSales" id="fenc_CostOfProductSales" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DilutiveEffectOfRestrictedShareUnits" id="fenc_DilutiveEffectOfRestrictedShareUnits" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TermOfExecutiveSeveranceInEventOfTermination" id="fenc_TermOfExecutiveSeveranceInEventOfTermination" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="RestrictedStockOptionsMember" id="fenc_RestrictedStockOptionsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OptionsToPurchaseCommonSharesMember" id="fenc_OptionsToPurchaseCommonSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="UnrealizedLossOnAvailableForSaleSecurities" id="fenc_UnrealizedLossOnAvailableForSaleSecurities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AllowanceForTradeCreditLossesPolicyTextBlock" id="fenc_AllowanceForTradeCreditLossesPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ConvertibleNotesToCommonStockMember" id="fenc_ConvertibleNotesToCommonStockMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ExecutiveSeveranceMonthsOfCurrentBaseSalaryPayable" id="fenc_ExecutiveSeveranceMonthsOfCurrentBaseSalaryPayable" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="EquityIncentivePlanAmendmentMember" id="fenc_EquityIncentivePlanAmendmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PerformanceShareUnitsMember" id="fenc_PerformanceShareUnitsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LicensingAgreementTable" id="fenc_LicensingAgreementTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LicenseAgreementLineItems" id="fenc_LicenseAgreementLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WeightedAverageExercisePriceOfWarrantsIssued" id="fenc_WeightedAverageExercisePriceOfWarrantsIssued" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NumberOfCustomersWithConcentrationRisk" id="fenc_NumberOfCustomersWithConcentrationRisk" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="RoyaltyRevenue" id="fenc_RoyaltyRevenue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ReclassificationsPolicyPolicyTextBlock" id="fenc_ReclassificationsPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ForeignFundsTranslatedIntoUsdMember" id="fenc_ForeignFundsTranslatedIntoUsdMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MarcoBrugheraMember" id="fenc_MarcoBrugheraMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TwoCustomersMember" id="fenc_TwoCustomersMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
</xsd:schema>
