Fennec Pharmaceuticals Inc.
PO Box 13628, 68 TW Alexander Drive
Research Triangle Park, NC 27709


December 13, 2023


Via EDGAR Correspondence


Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F. Street, N.E.

Washington D. C. 20549


Re:Acceleration of Effective Date
  Fennec Pharmaceuticals Inc.
  Registration Statement on Form S-3
  File No. 333-275452


Ladies and Gentlemen:


In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned respectfully requests that the effective date of the above-referenced Registration Statement be accelerated so that the same will become effective at 4:30 p.m., Eastern Time, on December 15, 2023, or as soon thereafter as is practicable.


Very truly yours,
 By:/s/ Rostislav Raykov                   
  Rostislav Raykov
  Chief Executive Officer