SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* MANCHESTER MANAGEMENT CO LLC (Last) (First) (Middle) 131 CHARLES STREET 1ST FLOOR (Street) BOSTON MA 02114 (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 11/22/2013	3. Issuer Name and Ticker or Trading Symbol ADHEREX TECHNOLOGIES INC [ ADHXF ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)	5. If Amendment, Date of Original Filed (Month/Day/Year)
			6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	2,933,650	I	See Footnote(1)
Common Stock	1,981,000	D(2)
Common Stock	328,000	D(3)
Common Stock	250,000	D(4)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Warrants	11/22/2013	11/22/2018	Common Stock	2,500,000	0.5	I	See Footnote(1)
Warrants	11/22/2013	11/22/2018	Common Stock	1,875,000	0.5	D(2)
Warrants	11/22/2013	11/22/2018	Common Stock	250,000	0.5	D(3)
Warrants	11/22/2013	11/22/2018	Common Stock	250,000	0.5	D(4)

1. Name and Address of Reporting Person* MANCHESTER MANAGEMENT CO LLC (Last) (First) (Middle) 131 CHARLES STREET 1ST FLOOR (Street) BOSTON MA 02114 (City) (State) (Zip)

1. Name and Address of Reporting Person* Manchester Explorer, L.P. (Last) (First) (Middle) 131 CHARLES STREET, 1ST FLOOR (Street) BOSTON MA 02114 (City) (State) (Zip)

1. Name and Address of Reporting Person* BESSER JAMES E (Last) (First) (Middle) C/O MANCHESTER MANAGEMENT COMPANY, LLC 131 CHARLES STREET, 1ST FLOOR (Street) BOSTON MA 02114 (City) (State) (Zip)

1. Name and Address of Reporting Person* FRANK MORGAN C. (Last) (First) (Middle) C/O MANCHESTER MANAGEMENT COMPANY, LLC 131 CHARLES STREET, 1ST FLOOR (Street) BOSTON MA 02114 (City) (State) (Zip)

Explanation of Responses:

1. Manchester Management Company, LLC, a Delaware limited liability company, provides investment management services to private individuals and institutions, including Manchester Explorer, L.P. The reported securities and warrants are indirectly beneficially owned by Manchester Management Company, LLC as a result of it having investment discretion over certain advisory accounts it manages. The reported securities and warrants may also be deemed to be indirectly beneficially owned by James E. Besser, as a Managing Member of Manchester Management Company, LLC, and by Morgan C. Frank, who serves as a portfolio manager and a consultant of Manchester Management Company, LLC. Each of the Reporting Persons disclaim beneficial ownership of the reported securities and warrants except to the extent of their pecuniary interest therein.

2. The reported securities and warrants are directly owned by Manchester Explorer, L.P., a Delaware limited partnership.

3. The reported securities and warrants are directly owned by James E. Besser in his personal capacity.

4. The reported securities and warrants are directly owned by Morgan C. Frank in his personal capacity.

	Manchester Management Company, LLC By: /s/ James E. Besser, Managing Member	11/27/2013
	Manchester Explorer, L.P. By: /s/ James E. Besser, Managing Member of the General Partner	11/27/2013
	James E. Besser By: /s/ James E. Besser	11/27/2013
	Morgan C. Frank By: /s/ Morgan C. Frank	11/27/2013
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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