Fennec Pharmaceuticals Inc.
PO Box 13628, 68 TW Alexander Drive
Research Triangle Park, NC 27709


November 6, 2020


Via EDGAR Correspondence


Jeffrey Gabor

Office of Life Sciences

Division of Corporation Finance

Securities and Exchange Commission

100 F. Street, N.E.

Washington D. C. 20549


Re:Acceleration of Effective Date

Fennec Pharmaceuticals Inc.

Registration Statement on Form S-3

File No. 333-249775


Dear Mr. Gabor:


In accordance with Rule 461 promulgated under the Securities Act of 1933, as amended (the “Securities Act”), Fennec Pharmaceuticals Inc. (the “Company”) hereby requests that the effective date of the above-referenced Registration Statement (the “Registration Statement”) be accelerated so that the Registration Statement becomes effective under the Securities Act by 2:00 p.m., Eastern Time, on November 10, 2020, or as soon thereafter as practicable.


  Very truly yours,  
  By: /s/ Rostislav Raykov     
    Rostislav Raykov  
    Chief Executive Officer