SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* Essetifin SPA (Last) (First) (Middle) VIA SUDAFRICA, 20 (Street) ROME L6 00144 (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 09/11/2017	3. Issuer Name and Ticker or Trading Symbol FENNEC PHARMACEUTICALS INC. [ FENC ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)	5. If Amendment, Date of Original Filed (Month/Day/Year) 09/21/2017
			6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	2,931,579	D(1)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* Essetifin SPA (Last) (First) (Middle) VIA SUDAFRICA, 20 (Street) ROME L6 00144 (City) (State) (Zip)

1. Name and Address of Reporting Person* Cavazza Enrico (Last) (First) (Middle) VIA SUDAFRICA, 20 (Street) ROME L6 00144 (City) (State) (Zip)

1. Name and Address of Reporting Person* Cavazza Silvia (Last) (First) (Middle) VIA SUDAFRICA, 20 (Street) ROME L6 00144 (City) (State) (Zip)

1. Name and Address of Reporting Person* Cavazza Francesca (Last) (First) (Middle) VIA SUDAFRICA, 20 (Street) ROME L6 00144 (City) (State) (Zip)

1. Name and Address of Reporting Person* Cavazza Preta Martina (Last) (First) (Middle) VIA SUDAFRICA, 20 (Street) ROME L6 00144 (City) (State) (Zip)

1. Name and Address of Reporting Person* CAVAZZA PAOLO (Last) (First) (Middle) VIA TESSERETE, 10 (Street) LUGANO V8 00000 (City) (State) (Zip)

Explanation of Responses:

1. Dispositive power over the shares of common stock owned by Essetifin S.p.A. is shared by Enrico Cavazza, Silvia Cavazza, Francesca Cavazza, Martina Cavazza Preta, and Paolo Cavazza. Each of Enrico Cavazza, Silvia Cavazza, Francesca Cavazza, Martina Cavazza Preta, and Paolo Cavazza disclaims beneficial ownership of all shares of common stock held by Essetifin S.p.A. except to the extent of any pecuniary interest therein.

Remarks:

This Form is being amended solely for the purpose of including the joint filers as signatories, which were omitted in the original filing pending receipt of EDGAR codes and to add the power of attorney, attached hereto. Exhibit List: Exhibit 24.1 - Power of Attorney Exhibit 24.2 - Power of Attorney Exhibit 24.3 - Power of Attorney Exhibit 24.4 - Power of Attorney Exhibit 24.5 - Power of Attorney Exhibit 99.1 - Joint Filers' Signatures

	Essetifin S.p.A. By: /s/ Marino Zigrossi	10/04/2017
	/s/ Marino Zigrossi for Enrico Cavazza by power of attorney	10/04/2017
	/s/ Marino Zigrossi for Silvia Cavazza by power of attorney	10/04/2017
	/s/ Marino Zigrossi for Francesca Cavazza by power of attorney	10/04/2017
	/s/ Marino Zigrossi for Martina Cavazza Preta by power of attorney	10/04/2017
	/s/ Fabio Poma for Paolo Cavazza by power of attorney	10/04/2017
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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Exhibit 24.1

 

POWER OF ATTORNEY

 

The undersigned does hereby constitute and appoint Marino Zigrossi, with full power of substitution, as the true and lawful attorney-in-fact and agent of the undersigned, and authorizes and designates him to sign on behalf of the undersigned, and to file filings and any amendments thereto, with the Securities and Exchange Commission, made by or on behalf of the undersigned in respect of the beneficial ownership of equity securities of REGENERX BIOPHARMACEUTICALS, INC.; SOLIGENIX, INC. and FENNEC PHARMACEUTICALS, INC. held by the undersigned, directly, indirectly or beneficially, pursuant to Sections 13(d), 13(g) and 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the rules and regulations thereunder. The undersigned acknowledges that the foregoing attorney-in-fact, in serving in such capacity at the request of the undersigned, is not assuming any of the undersigned's responsibilities to comply with Sections 13(d), 13(g) or 16 of the Exchange Act.

 

This Power of Attorney shall remain in full force and effect until withdrawn by the undersigned in a signed writing delivered to the foregoing attorney-in-fact.

 

IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 25th day of September 2017.

 

/s/ Enrico Cavazza
Enrico Cavazza

Exhibit 24.2

 

POWER OF ATTORNEY

 

The undersigned does hereby constitute and appoint Marino Zigrossi, with full power of substitution, as the true and lawful attorney-in-fact and agent of the undersigned, and authorizes and designates him to sign on behalf of the undersigned, and to file filings and any amendments thereto, with the Securities and Exchange Commission, made by or on behalf of the undersigned in respect of the beneficial ownership of equity securities of REGENERX BIOPHARMACEUTICALS, INC.; SOLIGENIX, INC. and FENNEC PHARMACEUTICALS, INC. held by the undersigned, directly, indirectly or beneficially, pursuant to Sections 13(d), 13(g) and 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the rules and regulations thereunder. The undersigned acknowledges that the foregoing attorney-in-fact, in serving in such capacity at the request of the undersigned, is not assuming any of the undersigned's responsibilities to comply with Sections 13(d), 13(g) or 16 of the Exchange Act.

 

This Power of Attorney shall remain in full force and effect until withdrawn by the undersigned in a signed writing delivered to the foregoing attorney-in-fact.

 

IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 25th day of September 2017.

  

/s/ Silvia Cavazza
Silvia Cavazza

Exhibit 24.3

 

POWER OF ATTORNEY

 

The undersigned does hereby constitute and appoint Marino Zigrossi, with full power of substitution, as the true and lawful attorney-in-fact and agent of the undersigned, and authorizes and designates him to sign on behalf of the undersigned, and to file filings and any amendments thereto, with the Securities and Exchange Commission, made by or on behalf of the undersigned in respect of the beneficial ownership of equity securities of REGENERX BIOPHARMACEUTICALS, INC.; SOLIGENIX, INC. and FENNEC PHARMACEUTICALS, INC. held by the undersigned, directly, indirectly or beneficially, pursuant to Sections 13(d), 13(g) and 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the rules and regulations thereunder. The undersigned acknowledges that the foregoing attorney-in-fact, in serving in such capacity at the request of the undersigned, is not assuming any of the undersigned's responsibilities to comply with Sections 13(d), 13(g) or 16 of the Exchange Act.

 

This Power of Attorney shall remain in full force and effect until withdrawn by the undersigned in a signed writing delivered to the foregoing attorney-in-fact.

 

IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 25th day of September 2017.

  

/s/ Francesca Cavazza
Francesca Cavazza

 

 

Exhibit 24.4

 

POWER OF ATTORNEY

 

The undersigned does hereby constitute and appoint Marino Zigrossi, with full power of substitution, as the true and lawful attorney-in-fact and agent of the undersigned, and authorizes and designates him to sign on behalf of the undersigned, and to file filings and any amendments thereto, with the Securities and Exchange Commission, made by or on behalf of the undersigned in respect of the beneficial ownership of equity securities of REGENERX BIOPHARMACEUTICALS, INC.; SOLIGENIX, INC. and FENNEC PHARMACEUTICALS, INC. held by the undersigned, directly, indirectly or beneficially, pursuant to Sections 13(d), 13(g) and 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the rules and regulations thereunder. The undersigned acknowledges that the foregoing attorney-in-fact, in serving in such capacity at the request of the undersigned, is not assuming any of the undersigned's responsibilities to comply with Sections 13(d), 13(g) or 16 of the Exchange Act.

 

This Power of Attorney shall remain in full force and effect until withdrawn by the undersigned in a signed writing delivered to the foregoing attorney-in-fact.

 

IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 25th day of September 2017.

 

/s/ Martina Cavazza Preta
Martina Cavazza Preta

 

Exhibit 24.5

 

POWER OF ATTORNEY

 

The undersigned does hereby constitute and appoint each of Fabio Poma and Nicola Wullschleger, with full power of substitution, as the true and lawful attorney-in-fact and agent of the undersigned, and authorizes and designates each of the foregoing attorneys-in-fact to sign on behalf of the undersigned, and to file filings and any amendments thereto, with the Securities and Exchange Commission, made by or on behalf of the undersigned in respect of the beneficial ownership of equity securities of FENNEC PHARMACEUTICALS, INC. held by the undersigned, directly, indirectly or beneficially, pursuant to Sections 13(d), 13(g) and 16 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and the rules and regulations thereunder. Each of the undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of each of the undersigned, are not assuming any of the undersigned's responsibilities to comply with Sections 13(d), 13(g) or 16 of the Exchange Act.

 

This Power of Attorney shall remain in full force and effect until withdrawn by the undersigned in a signed writing delivered to each of the foregoing attorneys-in-fact.

 

IN WITNESS WHEREOF, each of the undersigned has caused this Power of Attorney to be executed as of this 20th day of September 2017.

 

/s/ Paolo Cavazza
Paolo Cavazza

 

Exhibit 99.1

 

Joint Filers’ Signatures

 

ESSETIFIN S.P.A.

 

By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Director
Date:	October 2, 2017

 

Enrico Cavazza

 

By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Attorney-in-Fact
Date:	October 2, 2017

 

Silvia Cavazza

 

By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Attorney-in-Fact
Date:	October 2, 2017

 

Francesca Cavazza

 

By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Attorney-in-Fact
Date:	October 2, 2017

 

Martina Cavazza Preta

 

By:	/s/ Marino Zigrossi
Name:	Marino Zigrossi
Title:	Attorney-in-Fact
Date:	October 2, 2017

 

Paolo Cavazza

 

By:	/s/ Fabio Poma
Name:	Fabio Poma
Title:	Attorney-in-Fact
Date:	October 2, 2017